Selected Publications (Original Articles)

2021-2025

Kasikova, L., Rakova, J., Hensler, M. et al. Tertiary lymphoid structures and B cells determine clinically relevant T cell phenotypes in ovarian cancer. Nat Commun, 2024. 15: p. 2528.

Zhao, L., Liu, P., Mao, M., et al. BCL2 inhibition reveals a dendritic cell-specific immune checkpoint that controls tumor immunosurveillance. Cancer Discov, 2023. 13(11): p. 2448-2469.

Cultrara, C., Uhl, C., Kirby, K., et al. A biologic-device combination product delivering tumor-derived antigens elicits immunogenic cell death-associated immune responses against glioblastoma. J Immunother Cancer, 2023. 11(8): p. e006880. 

Sugita, M., Yamazaki, T., Alhomoud, M., et al. Radiation therapy improves CAR T cell activity in acute lymphoblastic leukemia. Cell Death Dis, 2023. 14(5): p. 305.

Holicek, P., Truxova, I., Rakova, J. et al. Type I interferon signaling in malignant blasts contributes to treatment efficacy in AML patients. Cell Death Dis, 2023. 14(3): p. 209.

Klapp, V., Buqué, A., Bloy, N. et al. Cellular senescence in the response of HR+ breast cancer to radiotherapy and CDK4/6 inhibitors. J Transl Med, 2023. 21: p. 110.

Clement, C.C., Osran, J., Buqué, A. et al. PDIA3 epitope-driven immune autoreactivity contributes to hepatic damage in type 2 diabetes. Sci Immunol, 2022. 7(74): p. eabl3795.

Fucikova, J., Hensler, M., Kasikova, L. et al. An autologous dendritic cell vaccine promotes anticancer immunity in ovarian cancer patients with low mutational burden and cold tumors. Clin Cancer Res, 2022. 28(14): p. 3053-3065.

Yamazaki, T., Wennerberg, E., Hensler, M. et al. LTX-315-enabled, radiotherapy-boosted immunotherapeutic control of breast cancer by NK cells. Oncoimmunology, 2021. 10(1): p. e1962592.

Montrose, D.C., Saha, S., Foronda, M. et al. Exogenous and endogenous sources of serine contribute to colon cancer metabolism, growth, and resistance to 5-fluorouracil. Cancer Res, 2021. 81(9): p. 2275-2288.

Morciano, G., Pedriali, G., Bonora, M. et al. A novel naturally occurring mutation in the glycine-rich domain of ATP synthase subunit c is associated with increased damage following hypoxia/reoxygenation in STEMI patients. Cell Rep, 2021. 35(2): p. 108983.

Clement, C.C., Nanaware, P.P., Yamazaki, T. et al. Pleiotropic consequences of metabolic stressors on the MHC class II antigen processing and presentation machinery. Immunity, 2021. 54(4): p. 721-736.

Petroni, G., Buqué, A., Yamazaki, T. et al. Radiotherapy delivered before CDK4/6 inhibitors mediates superior therapeutic effects in ER+ breast cancer. Clin Cancer Res, 2021. 27(7): p. 1855-1863.

Lhuillier, C., Rudqvist, N.-P., Yamazaki, T. et al. Radiotherapy-exposed CD8+ and CD4+ neoantigens enhance tumor control. J Clin Invest, 2021. 131(5): p. e138740.

Rakova, J., Truxova, I., Holicek, P. et al. TIM-3 levels correlate with enhanced NK cell cytotoxicity and improved clinical outcome in AML patients. Oncoimmunology, 2021. 10(1): p. e1889822.

2016-2020

Yamazaki, T., Kirchmair, A., Sato, A. et al. Mitochondrial DNA drives abscopal responses to radiation that are inhibited by autophagy. Nat Immunol, 2020. 21(10): p. 1160-1171.

Buqué, A., Bloy, N., Perez-Lanzón, M. et al. Immunoprophylactic and immunotherapeutic control of hormone receptor-positive breast cancer. Nat Comm, 2020. 11(1): p. 3819.

Truxova, I., Kasikova, L., Salek, C. et al. Calreticulin exposure on malignant blasts correlates with improved NK cell-mediated cytotoxicity in AML patients. Haematologica, 2020. 105(7): p. 1868-1878.

Yamazaki, T., Buqué, A., Ames, T.D. and L. Galluzzi. PT-112 induces immunogenic cell death and synergizes with immune checkpoint blockers in mouse tumor models. Oncoimmunology, 2020. 9(1): p. e1721810.

Kasikova, L., Hensler, M., Truxova, I. et al. Calreticulin exposure correlates with robust adaptive antitumor immunity and favorable prognosis in ovarian carcinoma patients. J Immunother Cancer, 2019. 7(1): p. 312.

Rodriguez-Ruiz, M.E., Buqué, A., Hensler, M. et al. Apoptotic caspases inhibit abscopal responses to radiation and identify a new prognostic biomarker for breast cancer patients. Oncoimmunology, 2019. 8(11): p. e1655964.

Bravo-San Pedro, J.M., Sica, V., Martins, I. et al. Acyl-CoA-binding protein is a lipogenic factor that triggers food intake and obesity. Cell Metabol, 2019. 30(4): p. 754-767.e9.

Fucikova, J., Rakova, J., Hensler, M. et al. TIM-3 dictates functional orientation of the immune infiltrate in ovarian cancer. Clin Cancer Res, 2019. 25(15): p. 4820-4831.

Tatsuno, K., Yamazaki, T., Hanlon, D. et al. Extracorporeal photochemotherapy induces bona fide immunogenic cell death. Cell Death Dis, 2019. 29(10): p. 578.

Sica, V., Bravo-San Pedro, J.M., Izzo, V. et al. Lethal poisoning of cancer cells by respiratory chain inhibition plus dimethyl a-ketoglutarate. Cell Rep, 2019. 27(3): p. 820-834.e9.

Pabla, S., Conroy, J.M., Nesline, M.K. et al. Proliferative potential and resistance to immune checkpoint blockade in lung cancer patients. J Immunother Cancer, 2019. 7(1): p. 27.

Conroy, J.M., Pabla, S., Nesline, M.K. et al. Next generation sequencing of PD-L1 for predicting response to immune checkpoint inhibitors. J Immunother Cancer, 2019. 7(1): p. 18.

Marchi, S., Corricelli, M., Branchini, A. et al. Akt-mediated phosphorylation of MICU1 regulates mitochondrial Ca2+ levels and tumor growth. EMBO J, 2019. 38(2): p. e99435.

Truxova, I., Kasikova, L., Hensler, M. et al. Mature dendritic cells correlate with favorable immune infiltrate and improved prognosis in ovarian carcinoma patients. J Immunother Cancer, 2018. 6(1): p. 139.

Morrison, C.D., Pabla, S., Conroy, J.M. et al. Predicting response to checkpoint inhibitors in melanoma beyond PD-L1 and mutational burden. J Immunother Cancer, 2018. 6(1): p. 32.

Bonora, M., Morganti, M., Morciano, G. et al. Mitochondrial permeability transition involves dissociation of F1FO ATP synthase dimers and C-ring conformation. EMBO Rep, 2017. 18(7): p. 1077-1089.

Fucikova, J., Truxova, I., Hensler, M. et al. Calreticulin exposure by malignant blasts correlates with robust anticancer immunity and improved clinical outcome in AML patients. Blood, 2016. 128(26): p. 3113-3124.

2011-2015

Niso-Santano, M., Malik, S.A., Pietrocola, F. et al. Unsaturated fatty acids induce non-canonical autophagy. EMBO J, 2015. 34(8): p. 1025-1041.

Ma, Y., Mattarollo, S.R., Adjemian, S. et al. CCL2/CCR2-dependent recruitment of functional antigen-presenting cells into tumors upon chemotherapy. Cancer Res, 2014. 74(2): p. 436-445.

Sukkurwala, A.Q., Martins, I., Wang, Y. et al. Immunogenic calreticulin exposure occurs through a phylogenetically conserved stress pathway involving the chemokine CXCL8. Cell Death Differ, 2014. 21(1): p. 59-68.

Jemaà, M., Galluzzi, L., Kepp, O. et al. Characterization of novel MPS1 inhibitors with preclinical anticancer activity. Cell Death Differ, 2013. 20(11): p. 1532-1545.

Lainey, E., Wolfromm, A., Marie, N. et al. Azacytidine and erlotinib exert synergistic effects against acute myeloid leukemia. Oncogene, 2013. 32(37): p. 4331-4342.

Ma, Y., Yamazaki, T., Yang, H. et al. Tumor necrosis factor is dispensable for the success of immunogenic anticancer chemotherapy. Oncoimmunology, 2013. 2(6): p. e24786.

Ma, Y., Adjemian, S., Mattarollo, S.R. et al. Anticancer chemotherapy induced intratumoral recruitment and differentiation of antigen presenting cells. Immunity, 2013. 38(4): p. 729-741.

Michels, J., Vitale, I., Galluzzi, L. et al. Cisplatin resistance associated with PARP hyperactivation. Cancer Res, 2013. 73(7): p. 2271-2280.

Bonora, M., Bononi, A., De Marchi, E. et al. Role of the c subunit of the FO ATP synthase in mitochondrial permeability transition. Cell Cycle, 2013. 12(4): p. 674-683.

Shen, S., Niso-Santano, M., Adjemian, S. et al. Cytoplasmic STAT3 represses autophagy by inhibiting PKR activity. Mol Cell, 2012. 48(5): p. 667-680.

Senovilla, L., Vitale, I., Martins, I. et al. An immunosurveillance mechanism controls cancer cell ploidy. Science, 2012. 337(6102): p. 1678-1684.

Galluzzi, L., Vitale, I., Senovilla, L. et al. Prognostic impact of vitamin B6 metabolism in lung cancer. Cell Rep, 2012. 2(2): p. 257-269.

Tailler, M., Senovilla, L., Lainey, E. et al. Antineoplastic activity of ouabain and pyrithione zinc in acute myeloid leukemia. Oncogene, 2012. 31(30): p. 3536-3546.

Menger, L., Vacchelli, E., Adjemian, S. et al. Cardiac glycosides exert anticancer effects by inducing immunogenic cell death. Sci Transl Med, 2012. 4(143): p. 143ra99.

Jemaà, M., Vitale, I., Kepp, O. et al. Selective killing of p53-deficient cancer cells by SP600125. EMBO Mol Med, 2012. 4(6): p. 500-514.

Michaud, M., Martins, I., Sukkurwala, A.Q. et al. Autophagy-dependent anticancer immune responses induced by chemotherapeutic agents in mice. Science, 2011. 334(6062): p. 1573-1577.

Criollo, A., Niso-Santano, M., Malik, S.A. et al. Inhibition of autophagy by TAB2 and TAB3. EMBO J, 2011. 30(24): p. 4908-4920.

Büttner, S., Ruli, D., Vögtle, F.N. et al. A yeast BH3-only protein mediates the mitochondrial pathway of apoptosis. EMBO J, 2011. 30(14): p. 2779-2792.

Zischka, H., Lichtmannegger, J., Schmitt, S. et al. Mitochondrial membrane crosslinking and destruction in a rat model for Wilson disease. J Clin Invest, 2011. 121(4): p. 1508-1518.

Morselli, E., Mariño, G., Bennetzen, M.V. et al. Spermidine and resveratrol induce autophagy by distinct pathways converging on the acetylproteome. J Cell Biol, 2011. 192(4): p. 615-629.

2006-2010

Vitale, I., Senovilla, L., Jemaà, M. et al. Multipolar mitosis of tetraploid cells: inhibition by p53 and dependency on Mos. EMBO J, 2010. 29(7): p. 1272-1284.

Galluzzi, L., Morselli, E., Vitale, I. et al. miR-181a and miR-630 regulate cisplatin-induced cancer cell death. Cancer Res, 2010. 70(5): p. 1793-1803.

Criollo, A., Senovilla, L., Authier, H. et al. The IKK complex contributes to the induction of autophagy. EMBO J, 2010. 29(3): p. 619-631.

Vicencio, J.M., Ortis, C., Criollo, A. et al. The inositol 1,4,5-trisphosphate receptor regulates autophagy through its interaction with Beclin 1. Cell Death Differ, 2009. 16(7): p. 1006-1017.

Boehrer, S., Adès, L., Tajeddine, N. et al. Suppression of the DNA damage response in acute myeloid leukemia versus myelodysplastic syndrome. Oncogene, 2009. 28(22): p. 2205-2218.

Tajeddine, N., Galluzzi, L., Kepp, O. et al. Hierarchical involvement of Bak, VDAC1 and Bax in cisplatin-induced cell death. Oncogene, 2008. 27(30): p. 4221-4232.

Hoffmann, J., Vitale, I., Buchmann, B. et al. Improved cellular pharmacokinetics and pharmacodynamics underlie the wide anticancer activity of sagopilone. Cancer Res, 2008. 68(13): p. 5301-5308.

Tasdemir, E., Maiuri, M.C., Galluzzi, L. et al. Regulation of autophagy by cytoplasmic p53. Nat Cell Biol, 2008. 10(6): p. 676-687.

Pauleau, A.L., Galluzzi, L., Scholz, S.R. et al. Unexpected role of the phosphate carrier in mitochondrial fragmentation. Cell Death Diff, 2008. 15(3): p. 616-618.

Vitale, I., Galluzzi, L., Vivet, S. et al. Inhibition of Chk1 kills tetraploid tumor cells through a p53-dependent pathway. PloS ONE, 2007. 2(12): p. e1337.

Zermati, Y., Mouhamad, S., Stergiou, L. et al. Non-apoptotic role for Apaf-1 in the DNA damage checkpoint. Mol Cell, 2007. 28(4): p. 624-637.

De La Motte Rouge, T., Galluzzi, L., Olaussen, K.A. et al. A novel EGFR inhibitor promotes apoptosis in non-small cell lung cancer cells resistant to erlotinib. Cancer Res, 2007. 67(13): p. 6253-6262.

Selected Publications (Review Articles)

2021-2025

De Martino, M., Rathmell, J.C., Galluzzi, L., at al. Cancer-cell metabolism in tumor-targeting immunity. Nat Rev Immunol, 2024. IN PRESS.

Galluzzi, L., Guilbaud, E., Schmidt, D., et al. Targeting immunogenic cell stress and death for cancer therapy. Nat Rev Drug Discov, 2024. IN PRESS. 

Dai, E., Chen, X., Linkermann, A., et al. A guideline on the molecular ecosystem regulating ferroptosis. Nat Cell Biol, 2024. IN PRESS.

Kroemer, G., Chan, T.A., Eggermont, A.M.M. and L. Galluzzi. Immunosurveillance in clinical cancer management. CA Cancer J Clin, 2023. IN PRESS.

Stern, L.J., Clement, C., Galluzzi, L. and L. Santambrogio. Non-mutational neoantigens in disease. Nat Immunol, 2024. 25(1): p. 29-40.

Galluzzi, L., Aryankalayil, MJ., Coleman, CN., et al. Emerging evidence for adapting radiotherapy to immunotherapy. Nat Rev Clin Oncol, 2023. 20(8): p.543-557.

Vitale, I., Pietrocola, F., Guilbaud, E., et al. Apoptotic cell death in disease – Current understanding of the NCCD 2023. Cell Death Differ, 2023. 30(5): p.1097-1154.

Marchi, S., Guilbaud, E., Tait, S.W.G., Yamazaki, T. and L. Galluzzi. Mitochondrial control of inflammation. Nat Rev Immunol, 2023. 23(2): p. 159-173.

López-Otín, C., Pietrocola, F., Roiz-Valle, D. et al. Meta-hallmarks of aging and cancer. Cell Metabol, 2023. 35(1): p. 12-35.

Tong, L., Jiménez-Cortegana, C., Tay, A.H.M. et al. NK cells and solid tumors: Therapeutic potential and persisting obstacles. Mol Cancer, 2022. 21(1): p. 206.

Petroni, G., Buqué, A., Coussens, L.M. and L. Galluzzi. Targeting oncogene and non-oncogene addiction to inflame the tumour microenvironment. Nat Rev Drug Discov, 2022. 22(6): p. 440-462.

Kroemer, G., Galassi, C., Zitvogel, L. and L. Galluzzi. Immunogenic cell stress and death. Nat Immunol, 2022. 23(4): p. 487-500.

Petroni, G., Cantley, L.C., Santambrogio, L., Formenti, S.C. and L. Galluzzi. Radiotherapy as a tool to elicit clinically actionable signalling pathways in cancer. Nat Rev Clin Oncol, 2022. 19(2): p. 114-131.

Klionsly, D.J., Petroni, G., Amaravadi, R.K. et al. Autophagy in major human diseases. EMBO J, 2021. 40(19): p. e108863.

Petroni, G., Buqué, A., Zitvogel, L., Kroemer, G. and L. Galluzzi. Immunomodulation by targeted anticancer agents. Cancer Cell, 2021. 39(3): p. 310-345.

Vitale, I., Shema, E., Loi, S. and L. Galluzzi. Intratumoral heterogeneity in cancer progression and response to immunotherapy. Nat Med, 2021. 27(2): p. 212-224.

2016-2020

Galluzzi, L., Humeau, J., Buqué, A., Zitvogel, L. and G. Kroemer. Immunostimulation by chemotherapy in the era of immune checkpoint blockers. Nat Rev Clin Oncol, 2020. 17(12): p. 725-741.

Petroni, G., Formenti, S.C., Chen-Kiang, S. and L. Galluzzi. Immunomodulation by anticancer cell cycle inhibitors. Nat Rev Immunol, 2020. 20(11): p. 669-679.

Marchi, S., Giorgi, C., Galluzzi, L. and P. Pinton. Ca2+ fluxes and cancer. Mol Cell, 2020. 78(6): p. 1055-1069.

Galluzzi, L., Vitale, I., Warren, S. et al. Consensus guidelines for the definition, detection and interpretation of immunogenic cell death. J Immunother Cancer, 2020. 8(1): p. e000337.

Rodriguez-Ruiz, M.E., Vitale, I., Harrington, K.J., Melero, I. and L. Galluzzi. Immunological impact of cell death signaling driven by radiation on the tumor microenvironment. Nat Immunol, 2020. 21(2): p. 120-134.

Vanpouille-Box, C., Hoffmann, J.A. and L. Galluzzi. Pharmacological modulation of nucleic acid sensors – Therapeutic potential and persisting obstacles. Nat Rev Drug Discov, 2019. 18(11): p. 845-867.

Deutsch, E., Chargary, C., Galluzzi, L. and G. Kroemer. Optimising efficacy and reducing toxicity of anticancer radioimmunotherapy. Lancet Oncol, 2019. 20(8): p. e452-e463.

Galluzzi, L. and D.R. Green. Autophagy-independent functions of the autophagy machinery. Cell, 2019. 177(7): p. 1682-1699.

Vitale, I., Manic, G., Coussens, L.M., Kroemer, G. and L. Galluzzi. Macrophages and metabolism in the tumor microenvironment. Cell Metab, 2019. 30(1): p. 36-50.

Bonora, M., Wieckowski, M.W., Sinclair, D.A. et al. Targeting mitochondria for cardiovascular disorders: therapeutic potential and obstacles. Nat Rev Cardiol, 2019. 16(1): p. 33-55.

Galluzzi, L., Yamazaki, T. and G. Kroemer. Linking intracellular adaptation to stress with organismal homeostasis. Nat Rev Mol Cell Biol, 2018. 19(11): p. 731-745.

Galluzzi, L., Chan, T., Kroemer, G., Wolchok, J.D. and A. López-Soto. The hallmarks of successful anticancer immunotherapy. Sci Transl Med, 2018. 10(459): p. eaat7807.

Vanpouille-Box, C., Demaria, S., Formenti, S.C. and L. Galluzzi. Cytosolic DNA sensing in organismal tumor control. Cancer Cell, 2018. 34(3): p. 361-378.

Galluzzi, L., Vanpouille-Box, C., Bakhoum, S.F. and S. Demaria. SnapShot: CGAS-STING signaling. Cell, 2018. 173(1): p. 276–276.e1.

Rybstein, M.D., Bravo-San Pedro, J.M., Kroemer, G. and L. Galluzzi. The autophagic network and cancer. Nat Cell Biol, 2018. 20(3): p. 243-251.

Galluzzi, L., Vitale, I., Aaronson, S.A. et al. Molecular mechanisms of cell death: Recommendations of the Nomenclature Committee on Cell Death 2018. Cell Death Differ, 2018. 25(3): p. 486-541.

Carmona-Gutierrez, D., Bauer, M.A., Zimmermann, A. et al. Guidelines and recommendations on yeast cell death nomenclature. Microb Cell, 2018. 5(1): p. 4-31.

Bantug, G., Galluzzi, L., Kroemer, G. and C. Hess. The spectrum of T cell metabolism in health and disease. Nat Rev Immunol, 2018. 18(1): p. 19-34.

López-Soto, A., Gonzalez, S., Smyth, M.J. and L. Galluzzi. Control of metastases by NK cells. Cancer Cell, 2017. 32(2): p. 135-154.

Galluzzi, L., Baehrecke, E.H., Ballabio, A. et al. Molecular definitions of autophagy and related processes. EMBO J, 2017. 36(13): p. 1811-1836.

Galluzzi, L., Bravo-San Pedro, J.M., Levine, B., Green, D.R. and G. Kroemer. Pharmacological modulation of autophagy: therapeutic potential and persisting obstacles. Nat Rev Drug Discov, 2017. 16(7): p. 487-511.

Vitale, I., Manic, G., De Maria, R., Kroemer, G. and L. Galluzzi. DNA damage in stem cells. Mol Cell, 2017. 66(3): p. 306-319.

Galluzzi, L., Bravo-San Pedro, J.M., Demaria, S., Formenti, S.C. and G. Kroemer. Activating autophagy to potentiate immunogenic chemotherapy and radiation therapy. Nat Rev Clin Oncol, 2017. 14(4): p. 247-258.

Galluzzi, L., Kepp, O., Chan, F.K. and G. Kroemer. Necroptosis: Mechanisms and relevance to disease. Annu Rev Pathol, 2017. 12: p. 103-130.

Galluzzi, L., Buqué, A., Kepp, O., Zitvogel, L. and G. Kroemer. Immunogenic cell death in cancer and infectious disease. Nat Rev Immunol, 2017. 17(2): p. 97-111.

López-Otín, C., Galluzzi, L., Freije, J.M.P., Madeo, F. and G. Kroemer. Metabolic control of longevity. Cell, 2016. 166(4): p. 802-821.

Galluzzi, L., Bravo-San Pedro, J.M., Blomgren, K. and G. Kroemer. Autophagy in acute brain injury. Nat Rev Neurosci, 2016. 17(8): p. 467-484.

Galluzzi, L., López-Soto, A., Kumar, S. and G. Kroemer. Caspases connect cell-death signaling to organismal homeostasis. Immunity, 2016. 44(2): p. 221-231.

2011-2015

Galluzzi, L., Buqué, A., Kepp, O., Zitvogel, L. and G. Kroemer. Immunological effects of conventional chemotherapy and targeted anticancer agents. Cancer Cell, 2015. 28(6): p. 690-714.

Kroemer, G., Senovilla, L., Galluzzi, L., André, F. and L. Zitvogel. Natural and therapy-induced immunosurveillance in breast cancer. Nat Med, 2015. 21(10): p. 1128-1138.

Sica, V., Galluzzi, L., Bravo-San Pedro, J.M., Izzo, V., Maiuri, M.C. and G. Kroemer. Organelle-specific initiation of autophagy. Mol Cell, 2015. 59(4): p. 522-539.

Pietrocola, F., Galluzzi, L., Bravo-San Pedro, J.M., Madeo, F. and G. Kroemer. Acetyl coenzyme A: a central metabolite and second messenger. Cell Metabol, 2015. 21(6): p. 805-821.

Zitvogel, L., Galluzzi, L., Kepp, O., Smyth, M.J. and G. Kroemer. Type I interferons in anticancer immunity. Nat Rev Immunol, 2015. 15(7): p. 405-414.

Galluzzi, L., Pietrocola, F., Bravo-San Pedro, J.M. et al. Autophagy in malignant transformation and cancer progression. EMBO J, 2015. 34(7): p. 856-880.

Zitvogel, L., Galluzzi, L., Viaud, S., Vétizou, M., Daillère, R., Merad, M. and G. Kroemer. Cancer and the gut microbiota: An unexpected link. Sci Transl Med, 2015. 7(271): p. 271ps1.

Galluzzi, L., Bravo-San Pedro, J.M., Vitale, I. et al. Essential versus accessory aspects of cell death: recommendations of the NCCD 2015. Cell Death Differ, 2015. 22(1): p. 58-73.

Galluzzi, L., Vacchelli, E., Bravo-San Pedro, J.M. et al. Classification of current anticancer immunotherapies. Oncotarget, 2014. 5(24): p. 12472-12508.

Kepp, O., Senovilla, L., Vitale, I. et al. Consensus guidelines for the detection of immunogenic cell death. Oncoimmunology, 2014. 3(9): p. e955691.

Galluzzi, L., Pietrocola, F., Levine, B. and G. Kroemer. Metabolic control of autophagy. Cell, 2014. 159(6): p. 1263-1276.

Galluzzi, L., Bravo-San Pedro, J.M. and G. Kroemer. Organelle-specific initiation of cell death. Nat Cell Biol, 2014. 16(8): p. 728-736.

Green, D.R., Galluzzi, L. and G. Kroemer. Metabolic control of cell death. Science, 2014. 345(6203): p. 1250256.

Galluzzi, L., Kepp, O., Vander Heiden, M.G. and G. Kroemer. Metabolic targets for cancer therapy. Nat Rev Drug Discov, 2013. 12(11): p. 829-846.

Ma, Y., Galluzzi, L., Zitvogel, L. and G. Kroemer. Autophagy in cellular immune responses. Immunity, 2013. 39(2): p. 211-227.

Brenner, C., Galluzzi, L., Kepp, O. and G. Kroemer. Decoding cell death signals in liver inflammation. J Hepatol, 2013. 59(3): p. 583-594.

Zitvogel, L., Galluzzi, L., Smyth, M.J. and G. Kroemer. Mechanism of action of conventional and targeted anticancer therapies: Reinstating immunosurveillance. Immunity, 2013. 39(1): p. 74-88.

Kroemer, G., Galluzzi, L., Kepp, O. and L. Zitvogel. Immunogenic cell death in cancer therapy. Annu Rev Immunol, 2013. 31: p. 51-72.

Galluzzi, L., Kepp, O. and G. Kroemer. Mitochondria: master regulators of danger signalling. Nat Rev Mol Cell Biol, 2012. 13(12): p. 780-788.

Galluzzi, L., Senovilla, L., Vitale, I. et al. Molecular mechanisms of cisplatin resistance. Oncogene, 2012. 31(15): p. 1869-1883.

Zitvogel, L., Kepp, O., Galluzzi, L. and G. Kroemer. Inflammasomes in carcinogenesis and anticancer immune responses. Nat Immunol, 2012. 13(4): p. 343-351.

Galluzzi, L., Senovilla, L., Zitvogel, L. and G. Kroemer. The secrete ally: immunostimulation by anticancer drugs. Nat Rev Drug Discov, 2012. 11(3): p. 215-233.

Galluzzi, L., Vitale, I., Abrams, J.M. et al. Molecular definitions of cell death subroutines: Recommendations of the Nomenclature Committee on Cell Death 2012. Cell Death Differ, 2012. 19(1): p. 107-120.

Green, D.R., Galluzzi, L. and G. Kroemer. Mitochondria and the autophagy-inflammation-cell death axis in organismal aging. Science, 2011. 333(6046): p. 1109–1112.

Vitale, I., Galluzzi, L., Castedo, M. and G. Kroemer. Mitotic catastrophe: a mechanism for avoiding genomic instability. Nat Rev Mol Cell Biol, 2011. 12(6): p. 385-392.

Kepp, O., Galluzzi, L., Lipinski, M., Yuan, J. and G. Kroemer. Cell death assays for drug discovery. Nat Rev Drug Discov, 2011. 10(3): p. 221-237.

2006-2010

Vandenabeele, P., Galluzzi, L., Vanden Berghe, T. and G. Kroemer. Molecular mechanisms of necroptosis: an ordered cellular explosion. Nat Rev Mol Cell Biol, 2010. 11(10): p. 700-714.

Fulda, S., Galluzzi, L. and G. Kroemer. Targeting mitochondria for cancer therapy. Nat Rev Drug Discov, 2010. 9(6): p. 447-464.

Galluzzi, L., Blomgren, K. and G. Kroemer. Mitochondrial membrane permeabilization in neuronal injury. Nat Rev Neurosci, 2009. 10(7): p. 481-494.

Kroemer, G., Galluzzi, L., Vandenabeele, P. et al. Classification of cell death: recommendations of the Nomenclature Committee on Cell Death. Cell Death Differ, 2009. 16(1): p. 3-11.

Kroemer, G., Galluzzi, L. and C. Brenner. Mitochondrial membrane permeabilization in cell death. Physiol Rev, 2007. 87(1): p. 99-163.

Independent Commentaries on our Work

Montes-Gómez, A.E. and S.W.G. Tait. J Transl Med. 2024. 22(1): p. 317. 

Martin S.J. Trends Immunol, 2023. 44(11): p. 871-873.

Booth C.A.G. and A.A. Lane. Trends Cancer, 2023. 9(12):p. 987-988.

Pol, J.G., Plantureux, C., Pérez-Lanzón, M. and G. Kroemer. Oncoimmunology, 2022. 11(1): p. 2130558.

Bird, L. Nat Rev Immunol, 2022. 22(10): p. 594-595.

Newman, J.H. and N. Bhardwaj. Trends Immunol, 2021. 42(4): p. 277-279.

Thorburn, A. Autophagy, 2020. 16(12): p. 2282-2284.

McArthur, K. and Kile B.T. Cell Death Discov, 2020. 6: p. 98.

Garg, A.D. and P. Agostinis. Oncotarget, 2020. 11(36): p. 3352-3353.

Kepp, O. and G. Kroemer. Oncoimmunology, 2020. 9(1): p. 1729022.

Melero, I. et al. Trends Cancer, 2020. 6(3): p. 173-174.

Kesavardhana, S. and T.-D. Kanneganti. Trends Immunol, 2019. 40(12): p. 1073-1075.

De Martino, M. and C. Vanpouille-Box. Trends Cell Biol, 2019. 29(11): p. 851-853.

Chinopoulos, C. EMBO Rep, 2017. 18(7): p. 1041-1042.

Hou, J., Greten. T.F. and Q. Xia. Nat Rev Immunol, 2017. 17(6): p. 401.

Jin, J. and S. He. Nat Rev Immunol, 2017. 17(2): p. 143.

Bankaitis, V.A. EMBO J, 2015. 34(8): p. 978-980.

Ruffell, B. and L. Coussens. Immunity, 2013. 38(4): p. 626-628.

Chinopoulos, C. and G. Szabadkai. Front Oncol, 2013. 3: p. 25.

Mahadevan, N.R. and M. Zanetti. Cell Cycle, 2013. 12(4): p. 544-545.

Alifano, M. and D. Damotte. Cell Cycle, 2013. 12(4): p. 543-544.

Du Toit, A. Nat Rev Mol Cell Biol, 2012. 13(12): p. 754.

Diederich, M. Cell Cycle, 2012. 11(22): p. 4109.

Minton, K. Nat Rev Immunol, 2012. 12(11): p. 745.

Zanetti, M. and N.R. Mahadevan. Science, 2012. 337(6102): p. 1616-1617.

Yao, Z. and G. Szabadkai. Cell Cycle, 2012. 11(20): p. 3721-3722.

Panaretakis, T. Cell Cycle, 2012. 11(20): p. 3723.

Calderón-Montaño, J.M., Burgos-Morón, E. and M. López-Lázaro. Oncogene, 2014. 33(22): p. 2947-2948.

Cianfanelli, V. and F. Cecconi. Cell Cycle, 2012. 11(3): p. 436-437.

Merle, U. and Stremmel W. Hepatology, 2011. 54(1):p. 358-60.

Amaravadi, R.K. Science, 2011. 334(6062): p. 1501-1502.

Gross, A. Cell Death Differ, 2011. 18(10): p. 1543-1544.

Oettinghaus, B., Frank, S. and L. Scorrano. EMBO J, 2011. 30(14): p. 2754-2756.

Chow, K.U. Cell Cycle, 2011. 15(10): p. 3050.

Merle, U. and W. Stremmel. Hepatology, 2011. 54(1): p. 358-360.

Carassa, L. Cell Cycle, 2010. 9(15): p. 2928.

Shieh, S.Y. Cell Cycle, 2010. 9(14): p. 2712.

Levine, B. and J. Abrams. Nat Cell Biol, 2008. 10(6): p. 637-639.

Sanchez-Olea, R and Yuan, J. Mol Cell, 2007. 28(4):p. 520-521.

For a complete list of peer-reviewed publications from Lorenzo Galluzzi, please click here

Make a gift

Give your help to cancer research.

Click here to make a secure gift by credit card.

With your support, we can make the difference.

Highlighted Articles