Biography

Claudia is currently a Post-Doctoral Associate with the Galluzzi Lab, in the Department of Radiation Oncology at Weill Cornell Medical College (New York), where she develops strategies to target cancer stem cells for circumventing the resistance of HR+ breast cancer to CDK4/6 inhibitors and radiation therapy. Prior to joining the Galluzzi Lab (2021), she was a Post-Doctoral Associate with the Demaria Lab, in the Department of General Pathology at Catholic University (Rome, Italy; Feb 2021-July 2021), under the supervision of Dr. Antonella Sistigu, after receiving her B.Sc. (2015) and M.Sc (2017), in Biological Sciences from Rome University “Tor Vergata” (Rome, Italy) and her Ph.D. in Oncological Sciences (2021) from at Catholic University. Claudia has a long-standing interest in understanding the immunological mechanisms whereby cancer stem cells evade immune recognition and elimination. 

(Co)-first Authored Publications 

  1. Galassi, C., Klapp, V., Yamazaki, T. et al. Molecular determinants of immunogenic cell death elicited by radiation therapy. Immunol Rev, 2024. 321(1): p. 20-32.
  2. Galassi, C., Klapp, V., Formenti, S.C., et al. Immunologically relevant effects of radiation therapy on the tumor microenvironment. Essays Biochem, 2023. 67(6): p. 979-989.
  3. Galassi C. and L. Galluzzi. Cancer stem cell immunoediting by IFNγ. Cell Death Dis, 2023. 14(8): p. 143.
  4. Galassi, C., and L. Galluzzi. Epigenetic escape of immunosurveillance by malignant cell precursors. EMBO J, 2023. 42(10):e114050.
  5. Galassi, C., Ruan, Y., Sato, A. et al. RT-PCR-assisted quantification of type I IFN responses in irradiated cancer cells. Methods Cell Biol, 2022. 172: p. 145-161.
  6. Galassi, C., Vitale, I. and L. Galluzzi. Using epigenetic modifiers to target cancer stem cell immunoevasion. Cancer Cell, 2021. 39(12): p. 1573-1575.  

(Co)-senior Authored Publications 

  1. Galassi, C., Klapp, V., Yamazaki, T. et al. Molecular determinants of immunogenic cell death elicited by radiation therapy. Immunol Rev, 2024. 321(1): p. 20-32

Abstracts Selected for Poster Presentation (First/co-first and last/co-last only) 

  1. Galassi C, Petroni G, Iribarren C, Galluzzi L. An immunological mechanism of resistance to CDK4/6 inhibitors in breast cancer. Keystone Symposium Cancer Immunotherapy: Beyond Immune Checkpoint Blockade and Overcoming Resistance (March 2024) 
  2. Galassi C, Petroni G, Iribarren C, Galluzzi L. An immunological mechanism of resistance to CDK4/6 inhibitors in breast cancer. Keystone Symposium Innate Immunity Across the Molecular, Cellular, Tissue and Therapeutic (April 2024)

Abstracts selected for Oral Presentation (First/co-first and last/co-last only)

1. Galassi C,. γδ T cells underlie resistance to CDK4/6 inhibitors in HR+ breast cancer. CIMT Summer School (September 2022).

Fellowships

  1. American Italian Cancer Foundation (AICF) 2023/2024 Post-doc Research Fellowship 
  2. American Italian Cancer Foundation (AICF) 2022/2023 Post-doc Research Fellowship

Other Achievements

  1. Arthur and Sandra Irving Cancer Immunology Symposium (2024) 
  2. SITC Women in Cancer Immunotherapy Network (WIN) Member (2023)
  3. Radiation Oncology-Biology Integration Network (ROBIN) Young Scientists Exchange Program (YSEP) Award (2023)
  4. CIMT Summer School Trainee (2022)

My Bibliography Link

https://www.ncbi.nlm.nih.gov/myncbi/1HUEiwwRI88Itd/bibliography/public/